FIG. 3.

Efficacies of CS-834 and reference antibiotics against pneumonia caused by penicillin-susceptible strain 2132. Each column and bar represents the mean ± standard error, respectively (n = 4 to 6). The indicated doses of each drug were administered orally twice daily for 2 days beginning at 24 h after infection, and the numbers of viable cells in the lungs (A) and blood (B) of mice were determined at 72 h after infection. CFTM-PI, cefteram pivoxil; CPDX-PR, cefpodoxime proxetil; CFDN, cefdinir; CDTR-PI, cefditoren pivoxil. The asterisks indicate a significant difference (P < 0.05) compared with the results for the control group.