TABLE 3.

Change in accommodative amplitude and facility by treatment group between successive examinations

Therapy	Vergence/Accommodative		Placebo
Time Intervals	Change† (95% CI)	P value	Change† (95% CI)	P value
Accommodative Amplitude (diopters)
Baseline to Week 4	6.1 (4.9 to 7.4)	<0.0001	3.1 (1.4 to 4.7)	0.004
Week 4 to Week 8	2.0 (0.8 to 3.2)	0.03	1.0 (−0.7 to 2.6)	0.99
Week 8 to Week 12	−0.3 (−1.5 to 1.0)	0.99	0.5 (−1.2 to 2.1)	0.99
Week 12 to Week 16	0.7 (−0.5 to 2.0)	0.99	0.6 (−1.1 to 2.2)	0.99
Baseline to Week 16	8.6 (7.4 to 9.8)	<0.0001	5.1 (3.4 to 6.7)	<0.0001
Accommodative Facility (cycles per minute)
Baseline to Week 4	5.9 (4.6 to 7.1)	<0.0001	4.1 (2.5 to 5.8)	<0.0001
Week 4 to Week 8	3.9 (2.7 to 5.2)	<0.0001	1.8 (0.1 to 3.5)	0.46
Week 8 to Week 12	2.8 (1.6 to 4.0)	0.0001	0.1 (−1.5 to 1.8)	0.99
Week 12 to Week 16	0.9 (−0.4 to 2.1)	0.97	1.6 (−0.1 to 3.2)	0.71
Baseline to Week 16	13.5 (12.2 to 14.7)	<0.0001	7.6 (6.0 to 9.3)	<0.0001

^†Change is computed as the mean value for the later visit minus the mean value for the earlier visit.

CI = confidence interval.