Table 3.

Prevalence of β-thalassemia in Northern Guangdong Province (n = 10,285).

Genotypes	Phenotype	Case number	Constituent ratio (%)	Prevalence ratio (%)
CD 41/42 (–TTCT)/N	β0/βN	234	35.89	2.28
IVS-II-654 (C > T)/N	β+/βN	218	33.44	2.12
CD 17 (A > T)/N	β0/βN	67	10.28	0.65
–28 (A > G)/N	β+/βN	63	9.66	0.61
CD 71/72 (+A)/N	β0/βN	24	3.68	0.23
CD 27/28 (+C)/N	β0/βN	14	2.15	0.14
βE(G > A)/N	β+/βN	13	1.99	0.13
CD 14/15 (+G)/N	β0/βN	5	0.77	0.05
–29 (A > G)/N	β+/βN	4	0.61	0.04
CAP +1 (A > C)/N	β+/βN	4	0.61	0.04
IVS-I-1 (G > T/A)/N	β0/βN	3	0.46	0.03
CD43 (G > T)/N	β0/βN	2	0.31	0.02
–80 (T > A)/N∗	β+/βN	1	0.15	0.01
Total		652	100.00	6.34

^∗A rare case with –80(T > A) homozygous mutation of β-thalassemia by Sanger sequencing.