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. 1998 Jan;42(1):45–52. doi: 10.1128/aac.42.1.45

FIG. 3.

FIG. 3

Pharmacokinetics of free and liposomal ciprofloxacin after i.v. administration. (A) Concentrations of ciprofloxacin in plasma after i.v. administration of free ciprofloxacin (•) or ciprofloxacin encapsulated in liposomes comprised of DPPC/chol (▪), DSPC/chol (▴), or SM/chol (⧫). The dose of ciprofloxacin injected for all treatments was 15 mg/kg. (B) Ciprofloxacin/lipid ratios in plasma after i.v. administration of the DPPC/chol (▪), DSPC/chol (▴), or SM/chol (⧫) formulation of liposomal ciprofloxacin. Data represent means ± standard errors from three mice.