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. 2023 Aug 14;78(10):2442–2450. doi: 10.1093/jac/dkad249

Figure 3.

Figure 3.

Model structure of CMY-185. (a) Overall structure of CMY-185. The substitution residues are shown as CPK representations coloured in magenta. To clarify the substrate-binding site, the ceftazidime molecule is shown as a white ball-and-stick representation. (b, c) Close-up views of the model structures of the CMY-185 complex with ceftazidime (b) or avibactam (c). (d, e) Close-up views of the crystal structures of the AmpCEnt385 complex with ceftazidime (d, PDB accession number 6LC9) or avibactam (e, PDB accession number 6LC8). Hydrogen bonds are represented as orange dashed lines.