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. 2023 Sep 1;55(9):1982–1995. doi: 10.1038/s12276-023-01079-w

Table 1.

Regulation of cholesterol metabolism by noncoding RNA.

ncRNA Targets Mechanism References
miR-128-1 ABCA1, LDLR Regulation of efflux and uptake 72
miR-148a ABCA1, LDLR Regulation of efflux and uptake 72,73
miR-130b ABCA1, LDLR Regulation of efflux and uptake 72,74
miR-301b ABCA1, LDLR Regulation of efflux and uptake 72
miR-185, SR-B1 Regulation of selective uptake of HDL-c 74,75
miR-96 SR-B1 Regulation of selective uptake of HDL-c 75
miR-223 SR-B1 Regulation of selective uptake of HDL-c 75
miR-24 SR-B1 Regulation of cholesterol uptake 76
miR-33 SREBP2, ABCA1 Upstream of ABCA1 77,78
miR-183 ABCA1 Regulation cholesterol efflux 79,80
miR-26 ABCA1 Regulation cholesterol efflux 84
miR-20a/b, ABCA1 Regulation cholesterol efflux 81
miR-758 ABCA1 Regulation cholesterol efflux 83
miR-19b ABCA1 Regulation cholesterol efflux 82
miR-129-5p ABCG1 Upregulation of ABCG1 expression 85
lncARSR SREBP-2, HMGCR Upregulation of SREBP-2 and HMGCR expression 86
HULC RXRA Downregulation of miR-9 expression and upregulation of RXRA expression 87
NEAT1 miR-342-3p Modulation of immune cell functions and lipid uptake 88
ANRIL Unknown Modulation of the inflammatory response 89
MALAT1 ABCA1 Regulation of cholesterol accumulation 90