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. 2023 Oct 2;14:6137. doi: 10.1038/s41467-023-41881-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a, b Volcano plot of piRNA expression in premotor and motor stages of PD patients. Data were obtained from GEO database (GSE97285) which includes 7 early premotor PD, 7 late motor stage PD, and 14 control samples. Red dots, P value < 0.01; orange dots, |log2(fold change)| > 1; blue dots, P value < 0.01 and |log2(fold change)| > 1; black dots, P value ≥ 0.01 and |log₂(fold change)| ≤ 1. Data are provided in Supplementary Data 6.