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. 2023 Oct 1;19(10):1811–1822. doi: 10.5664/jcsm.10698

Figure 1. Timeline of the entire study.

Figure 1

DBRWP = double-blind randomized withdrawal period, LXB = low-sodium oxybate, OLE = open-label extension, OLT = open-label titration and optimization period, SDP = stable-dose period, SXB = high-sodium oxybate. Modified from Dauvilliers Y, Arnulf I, Foldvary-Schaefer N, et al. Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomized withdrawal study. Lancet Neurol. 2022;21(1):53-65. doi:10.1016/S1474-4422(21)00368-9, with permission from Elsevier.