Figure 5. Change in PGIc ratings from baseline to OLT W1 and end of the SDP and during the OLE.

Categories with zero responses are not shown. ^amITT population excludes participants taking high-sodium oxybate at study entry. Time points prior to the OLE include the total mITT population. mITT = modified intent-to-treat, OLE = open-label extension period, OLT = open-label titration and optimization period, PGIc = Patient Global Impression of Change, SDP = stable-dose period, W = week.