Table 2.

Oncolytic vaccinia virus strains and mutations studied for cancer treatment

Strain	Modification	Representative viruses	Insertions (Ref)
Wyeth	J2R-	Pexa-vec	GM-CSF45
WR	J2R-, VGF-	vvDD	GFP46
Lister	J2R-, F14.5L-, A56R-	GL-ONC1	Renilla luciferase-GFP fusion protein, β-galactosidase, β-glucuronidase74
	VGF-, O1L-	ASP9801	IL-7/IL1257
Tian Tan Guang 9	J2R-	VG9	GM-CSF; IL-2495
Copenhagen	J2R-, I4L-	TG-6002	FCU-123
New York City Board of Health	5p, 3p, and B14R	vaccinia virus-aCEA TCE	aCEA T cell engagers29