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. 2023 Sep 5;308(3):e223255. doi: 10.1148/radiol.223255

Figure 3:

In vivo MR spectra acquired with a point-resolved spectroscopy sequence optimized for D-2-hydroxyglutarate detection (echo time, 97 msec) in 18 patients with isocitrate dehydrogenase 1–mutant noncodeleted gliomas. The volumes of interest (red boxes) are shown on axial three-dimensional fluid-attenuation inversion-recovery images. Patients (P) 14–24 were included at site 1 (Centre for Neuroimaging Research Pitié-Salpêtrière Hospital, Paris, France). Patients 25–31 were included at site 2 (Spedali Civili University Hospital, Brescia, Italy). Demographic and clinical characteristics are summarized in Table 1. ppm = parts per million.

In vivo MR spectra acquired with a point-resolved spectroscopy sequence optimized for D-2-hydroxyglutarate detection (echo time, 97 msec) in 18 patients with isocitrate dehydrogenase 1–mutant noncodeleted gliomas. The volumes of interest (red boxes) are shown on axial three-dimensional fluid-attenuation inversion-recovery images. Patients (P) 14–24 were included at site 1 (Centre for Neuroimaging Research Pitié-Salpêtrière Hospital, Paris, France). Patients 25–31 were included at site 2 (Spedali Civili University Hospital, Brescia, Italy). Demographic and clinical characteristics are summarized in Table 1. ppm = parts per million.