Skip to main content
. 2023 Oct 2;177(11):1197–1205. doi: 10.1001/jamapediatrics.2023.4003

Table 2. Baseline and Outcome Functional Assessment Measures for Total Sample and by ASD Status.

Standard scores Diagnostic group, mean (SD) score Statistical analysisa Effect size, Cohen d
All (n = 213) Nonpersistent ASD (n = 79) Persistent ASD (n = 134)
Baseline clinical measures at 12-36 mo of age
Cognitiveb 81.67 (14.03) 85.99 (11.39) 79.11 (14.84) t = 3.785 0.50
Bayley-III Languagec 65.49 (16.02) 70.91 (16.47) 62.25 (14.90) t = 3.533 0.56
Vineland Adaptive Behavior Scales composited 73.52 (10.20) 77.81 (9.77) 71.04 (9.64) t = 4.587 0.70
Research-administered outcome measures at 5-7 y of age
Cognitivee 89.83 (26.42) 105.22 (12.73) 80.76 (28.18) t = 8.657 1.12
Score <70 46 0 46 χ2 = 34.589 0.88
Score >70 167 79 88
Vineland Adaptive Behavior Scales
Composite 82.39 (18.34) 94.68 (12.08) 75.14 (17.55) t = 9.597 1.24
Communication 82.27 (22.46) 95.39 (12.55) 74.53 (23.43) t = 8.454 1.03
Daily living skills 82.78 (15.85) 92.73 (12.50) 76.92 (14.68) t = 8.015 1.14
Socialization 85.52 (20.85) 99.66 (10.40) 77.18 (20.98) t = 10.418 1.26
Motorf 87.11 (12.23) 94.53 (8.84) 82.71 (11.84) t = 8.270 1.09
PLS-5 standard scores
Total languageg 91.05 (24.35) 108.33 (12.20) 80.71 (23.97) t = 11.059 1.36
Auditory comprehensionh 89.60 (22.40) 105.09 (11.26) 80.33 (22.31) t = 10.678 1.31
Expressive communication 91.55 (25.12) 108.80 (12.37) 81.23 (25.18) t = 10.617 1.29

Abbreviations: ASD, autism spectrum disorder; Bayley-III, Bayley Scales of Infant and Toddler Development, Third Edition; PLS-5, Preschool Language Scales–Fifth Edition.

a

P < .001 for all.

b

Two hundred eleven children completed Bayley-III Cognitive and 1 completed Differential Ability Scales (DAS) general cognitive ability at baseline clinical assessment; 1 was missing this variable.

c

Data were missing for 42 children.

d

Data were missing for 27 children.

e

One hundred ninety-seven children completed the DAS; for the 16 who completed Bayley-III, a developmental quotient was calculated as proxy for cognitive score. For cognitive scores at outcome, both mean (SD) and scores dichotomized to less than 70 vs 70 or greater are presented.

f

Data were missing for 1 child.

g

Data were missing for 3 children.

h

Data were missing for 2 children.