Table 3. Logistic Regression Associated With Nonpersistent vs Persistent ASD.
| Predictive factors | Nonpersistent vs persistent ASD | |||
|---|---|---|---|---|
| b Coefficient (SE)a | z Test | P value | OR (95% CI) | |
| Age at clinical ASD diagnosis | −0.116 (0.069) | −1.669 | .09 | 0.94 (0.87-1.01) |
| Age at research assessment | 0.067 (0.072) | 0.930 | .35 | 1.02 (0.98-1.07) |
| Sex, male | −0.239 (0.064) | −3.756 | <.001 | 0.27 (0.13-0.53) |
| Maternal education level | −0.088 (0.077) | −1.150 | .25 | 0.89 (0.72-1.09) |
| Baseline Bayley-III cognitive standard score | 0.041 (0.120) | −0.337 | .74 | 0.99 (0.96-1.03) |
| Baseline Bayley-III language standard score | −0.081 (0.114) | −0.710 | .48 | 0.99 (0.96-1.02) |
| Baseline Vineland Adaptive Behavior Scales composite standard score | −0.287 (0.108) | −2.651 | .008 | 0.94 (0.90-0.99) |
| Insurance status | −0.029 (0.076) | −0.381 | .70 | 0.90 (0.52-1.56) |
| Receipt of total interventionsb | −0.056 (0.066) | −0.855 | .39 | 0.99 (0.97-1.01) |
| Receipt of ASD-specific interventions | −0.003 (0.059) | −0.052 | .96 | 1.00 (0.98-1.02) |
| Receipt of ABA interventions | −0.039 (0.056) | −0.702 | .48 | 0.99 (0.97-1.01) |
Abbreviations: ASD, autism spectrum disorder; ABA, applied behavioral analysis; Bayley-III, Bayley Scales of Infant and Toddler Development, Third Edition; OR, odds ratio.
The SE of estimates were adjusted for the autocorrelation induced by the nesting of participants within 44 different combinations of developmental-behavioral pediatrician and psychologist assessment groups at baseline ASD clinical diagnoses.
The intervention variables have been included separately in the model as they were colinear (rs > 0.95). Thus, the coefficients in the model reflect a multivariate model with total interventions. The estimates for ASD-specific and ABA interventions reflect different model runs, albeit with almost identical estimates for the rest of the variables. Intervention variables represent maximal intensity of intervention following ASD diagnosis, operationalized as the highest number of hours per week of intervention for each participant received in any of the first three 6-month blocks after ASD diagnosis.