Table 5.
Subgroup analysis of the effect of body mass index on mortality among all the enrolled patients with pulmonary tuberculosis.
| Univariable analysis | Multivariable analysis | BMI *Sex | Male | Female | ||
|---|---|---|---|---|---|---|
| cOR (95% CI) | aOR (95% CI) | Coef | P -value | aOR (95% CI) | aOR (95% CI) | |
| (A) Underweight group | ||||||
| All cause of death | 2.139 (1.848–2.476) | 1.951 (1.674–2.274) | −0.171 | 0.295 | 2.078 (1.717–2.514) | 1.724 (1.332–2.231) |
| TB-related death | 2.354 (1.777–3.120) | 2.057 (1.546–2.735) | −0.168 | 0.567 | 2.245 (1.543–3.266) | 1.765 (1.135–2.746) |
| Non-TB-related death | 1.902 (1.611–2.246) | 1.719 (1.446–2.042) | −0.154 | 0.409 | 1.812 (1.465–2.241) | 1.554 (1.155–2.092) |
| (B) Overweight group | ||||||
| All cause of death | 0.801 (0.681–0.943) | 0.755 (0.639–0.893) | 0.042 | 0.813 | 0.743 (0.604–0.915) | 0.781 (0.588–1.037) |
| TB-related death | 0.684 (0.477–0.981) | 0.692 (0.482–0.995) | −0.491 | 0.210 | 0.824 (0.525–1.292) | 0.500 (0.268–0.934) |
| Non-TB-related death | 0.849 (0.709–1.018) | 0.793 (0.659–0.955) | 0.209 | 0.290 | 0.739 (0.587–0.930) | 0.919 (0.672–1.257) |
(A) Underweight group id compared to the normal weight group. (B) Overweight group is compared to the normal weight group. BMI, body mass index; cOR, crude odds ratio; CI, confidence interval; aOR, adjusted odds ratio; Coef, coefficient; AFB, acid-fast bacilli; TB, tuberculosis. The odds ratios for each outcome were calculated using logistic regression. Multivariate analysis is adjusted for age, sex, current smoking status, heavy alcohol intake, and the presence of underlying comorbidities. Reference to normal weight (18.5 kg/m2 ≤ BMI < 23 kg/m2).
*
Interaction analysis between BMI and sex.