TABLE 1.
Reasons for withdrawal
| Reason for withdrawal | No. (%) of patients
|
|||
|---|---|---|---|---|
| Grepafloxacin
|
Ciprofloxacin at 500 mg twice daily (n = 213) | Overall (n = 624) | ||
| 400 mg once daily (n = 207) | 600 mg once daily (n = 204) | |||
| Lack of responsea | 8 (4) | 13 (6) | 20 (9) | 41 (7) |
| Adverse event | 6 (3) | 8 (4) | 6 (3) | 20 (3) |
| General unwillingness to participate | 2 (1) | 4 (2) | 2 (1) | 8 (1) |
| Lost to follow-up | 4 (2) | 4 (2) | 1 (0.5) | 9 (1) |
| Noncomplianceb | 2 (1) | 1 (0.5) | 4 (2) | 7 (1) |
| Other | 10 (5) | 7 (3) | 7 (3) | 24 (4) |
| Total | 32 (16) | 37 (18) | 40 (19) | 109 (18) |
a
Assessed as treatment failures.
b
Defined as failure to take at least 80% of the first 7 days of medication or failure to report for at least three of the four required during-treatment and posttreatment clinic visits.