TABLE 5.
Most frequently reported drug-related treatment-emergent adverse eventsa
| Adverse event | No. (%) of patients
|
||
|---|---|---|---|
| Grepafloxacin at 400 mg once daily (n = 207) | Grepafloxacin at 600 mg once daily (n = 204) | Ciprofloxacin at 500 mg twice daily (n = 213) | |
| Nausea | 30 (15) | 45 (22%)b | 27 (13%)b |
| Taste perversion | 26 (13)c,d | 54 (27%)d,e | 8 (4%)c,e |
| Headache | 16 (8) | 16 (8) | 23 (11) |
| Dizziness | 17 (8) | 19 (9) | 12 (6) |
| Diarrhea | 12 (6) | 14 (7) | 14 (7) |
| Vomiting | 4 (2)f | 18 (9)f | 9 (4) |
P values are provided only where significant differences were observed.
P = 0.014.
P = 0.001.
P < 0.001.
P < 0.001.
P = 0.002.