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. 2022 Dec 10;2(1):100054. doi: 10.1016/j.focus.2022.100054

Table 4.

Summary of Meta-analysis Results by Types of Outcome and Exposure

Outcome and exposure measures Pooled results
n HR 95% CI Heterogeneity
I2 (%) p-value
Outcome 1: cardiovascular disease mortality
 Activity intensity
  1. Total PA 3 0.29 0.18–0.47 0.0 0.547
  2. Moderate-to-vigorous PA 4 0.37 0.25–0.55 9.3 0.347
  3. Light PA 3 0.62 0.41–0.93 0.0 0.410
  4. Sedentary behavior 3 1.89 1.09–3.29 34.7 0.216
 Step count
  Steps per day 1 a a
Outcome 2: all-cause mortality
Main analysis
 Activity intensity
  1. Total PA 6 0.42 0.34–0.53 4.4 0.389
  2. Moderate-to-vigorous PA 11 0.43 0.35–0.53 31.8 0.136
  3. Light PA 8 0.58 0.43–0.80 50.5 0.049
  4. Sedentary behavior 7 1.58 1.19–2.09 61.7 0.007
 Step count
  Steps per day 4 0.35 0.29–0.42 0.0 0.874
Additionalb analysis
 Activity intensity
  1. Total PA 6 0.42 0.34–0.53 4.4 0.389
  2. Moderate-to-vigorous PA 6 0.41 0.33–0.51 0.0 0.494
  3. Light PA 6 0.54 0.33–0.90 63.6 0.017
a

Less than 2 observations were available.

b

Included only studies that reported outcomes for total PA, moderate-to-vigorous intensity PA, and light-intensity PA.

HR, hazard ratio; N, number of observation point; PA, physical activity.