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. 2023 Oct 3;6:0247. doi: 10.34133/research.0247

Fig. 4.

Fig. 4.

PLMDs plus RT enhanced the infiltration of antitumor immune cells while suppressing the infiltration of tumor-promoting immune cells in TRAMP-C2 tumor tissues. Immunofluorescent images and quantification of iNOS+ M1 macrophages (A) and CD8+ cytotoxic T cells (B). (C) Immunofluorescence staining of CD11b+ and GR-1+ colocalization (MDSCs) and (D) FOXP3+ (Tregs). Quantification of image data for the indicated markers compared to saline control (n = 3), PLMDs alone (n = 4), RT alone (n = 4), and PLMDs + RT (n = 5). Scale bars, 200 μm. Data are presented as means ± SD. P < 0.05 (*), P < 0.005 (**), P < 0.0005 (***), and P < 0.0001 (****).