Table 1.
Incidence rate ratio (IRR) with 95% confidence intervals (CI) for COVID-19 related hospital admission within at-risk industrial sectors1across pandemic waves and between at-risk industrial sectors in comparison with a COVID-19 job exposure matrix (JEM)-based reference group.
Occupations Within and between group difference | DB07 code | All waves | Wave 1 week 8–32 2020 (Alpha variant) | Wave 2 week 33–52 2021, 1-4 2021 (Alpha variant) | Wave 3 week 5–26 2021 (Beta variant) | Wave 4 week 27–50 2021 (Delta variant) | Test for trend 2/interaction 3 | ||||||||||
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N | IRR | 95% CI | N | IRR | 95% CI | N | IRR | 95% CI | N | IRR | 95% CI | N | IRR | 95% CI | P-value | ||
Healthcare | 85 | 314 | 102 | 120 | 42 | 50 | |||||||||||
Within 2 | - | - | 1.00 | 1.23 | 1.0-1.6 | 0.47 | 0.3-0.7 | 0.52 | 0.4-0.7 | <0.0001 | |||||||
Between 3 | 1.66 | 1.4-1.9 | 3.59 | 2.7-4.9 | 1.64 | 1.3-2.1 | 0.94 | 0.7-1.3 | 1.19 | 0.9-1.7 | <0.0001 | ||||||
Social care | 87–88 | 628 | 95 | 251 | 117 | 165 | |||||||||||
Within 2 | - | - | 1.00 | 2.76 | 2.2-3.5 | 1.41 | 1.1-1.9 | 1.82 | 1.4-2.4 | <0.0001 | |||||||
Between3 | 1.40 | 1.2-1.6 | 1.51 | 1.1-2.1 | 1.45 | 1.2-1.8 | 1.09 | 0.9-1.4 | 1.58 | 1.2-2.0 | 0.069 | ||||||
Education | 86 | 226 | 22 | 89 | 58 | 57 | |||||||||||
Within 2 | - | - | 1.00 | 4.24 | 2.7-6.8 | 3.02 | 1.9-4.9 | 2.72 | 1.7-4.5 | <0.0001 | |||||||
Between 3 | 1.31 | 1.1-1.5 | 0.80 | 0.5-1.3 | 1.30 | 1.0-1.7 | 1.43 | 1.1-2.0 | 1.60 | 1.2-2.2 | 0.185 | ||||||
Transport | 49-51 | 128 | 17 | 42 | 46 | 23 | |||||||||||
Within 2 | - | - | 1.00 | 2.60 | 1.5-4.6 | 3.10 | 1.8-5.5 | 1.44 | 0.8-2.7 | <0.0001 | |||||||
Between 3 | 1.85 | 1.5-2.3 | 1.69 | 1.0-2.9 | 1.44 | 1.0-2.0 | 2.73 | 1.9-3.9 | 1.77 | 1.1-2.8 | 0.051 | ||||||
Retail sales | 46 | 120 | 12 | 44 | 24 | 40 | |||||||||||
Within 2 | 1.00 | 3.83 | 2.0-7.3 | 2.29 | 1.1-4.6 | 3.49 | 1.8-6.7 | <0.0001 | |||||||||
Between 3 | 1.01 | 0.8-1.2 | 0.93 | 0.5-1.7 | 1.09 | 0.8-1.5 | 0.84 | 0.5-1.3 | 1.13 | 0.8-1.6 | 0.037 | ||||||
Service trades | 55, 56, 81, 93, 96 | 213 | 21 | 83 | 63 | 46 | |||||||||||
Within 2 | - | - | 1.00 | 4.16 | 2.6-6.7 | 3.46 | 2.1-5.7 | 2.32 | 1.4-3.9 | <0.0001 | |||||||
Between 3 | 0.93 | 0.8-1.1 | 0.78 | 0.5-1.3 | 0.97 | 0.8-1.2 | 1.09 | 0.8-1.5 | 0.78 | 0.6-1.1 | 0.160 | ||||||
Others4 | 1535 | 216 | 531 | 422 | 366 | ||||||||||||
Within 2 | - | - | 1.00 | 2.58 | 2.2-3.0 | 2.24 | 1.9-2.6 | 1.78 | 1.5-2.1 | <0.0001 | |||||||
Between 3 | 0.94 | 0.9-1.0 | 0.91 | 0.7-1.2 | 0.80 | 0.7-0.9 | 1.09 | 0.9-1.3 | 1.08 | 0.9-1.3 | 0.065 | ||||||
Missing DISCO-08 code | 693 | 76 | 224 | 183 | 210 | ||||||||||||
Within 2 | - | 1.00 | 3.10 | 2.4-4.0 | 2.77 | 2.1-3.6 | 2.92 | 2.3-3.8 | <0.0001 | ||||||||
Between 3 | 1.15 | 1.0-1.3 | 0.94 | 0.7-1.3 | 0.97 | 0.8-1.2 | 1.25 | 1.0-1.6 | 1.48 | 1.2-1.9 | <0.0001 | ||||||
JEM-based reference group 3 | 559 | 1.0 | 83 | 1.00 | 224 | 2.84 | 2.2-3.7 | 133 | 1.84 | 1.4-2.4 | 118 | 1.49 | 1.1-2.0 | <0.0001 |
Industrial sectors at the 2-digit DB07 level with a higher likelihood of occupational SARS-CoV-2 exposure according to an expert rated COVID-19 job exposure matrix (sumscore >12, range 0-24) (9).
Crude risk across pandemic waves within each group of occupations relative to the occurrence in the first wave. P-values for test of non-linear trend in risk across waves (within industrial sector comparisons).
Wave-specific risk adjusted for sex, age (10 year groups), duration of education at baseline (5 groups), number of hospital admissions for one or more of 11 chronic diseases in the 10 years preceding start of the pandemic (0, 1, >1), country of origin (4 categories) and geographical region (5 groups) in an at-risk industrial sector compared with a COVID-19 JEM reference group (9) (all employees with low likelihood of occupational SARS-CoV-2 exposure (sumscore for all eight rated measures = 0)). P-values for interaction testing if the pandemic wave modified the effect of industrial sector on risk of COVID-19 hospital admission (between industrial sector comparisons).
Employees in other industrial sectors and employees with COVID-19 JEM sumscore ≤12.