Table 2.
Patient serologic responses to single dose of intratumoral HSV1716.
| Patient | WBC | ALC | ANC | HSV-1 PCR | HSV-1 IgG | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Day | 0 | 0 | 0 | 0 and 1 | 4 | 7 | 14 | 21 | 28 | Baseline | 28 |
| HSV01 | 4.9 | 686 | 3626 | - | - | - | - | - | - | - | + |
| HSV02 | 4.7 | 1739 | 1692 | - | - | - | - | - | - | + | + |
| HSV03 | 6 | 1140 | 4140 | - | + | - | - | - | - | - | + |
| HSV04 | 3 | 600 | 2040 | - | + | + | + | + | + | - | + |
| HSV05 | 4.4 | 1408 | 2640 | - | - | - | - | - | - | - | - |
| HSV06 | 8 | 1040 | 5600 | - | + | - | - | - | - | - | - |
| HSV07 | 6 | 1260 | 4080 | - | + | - | - | - | - | - | ND |
| HSV08 | 4.3 | 1419 | 2451 | - | + | - | - | - | - | - | + |
| HSV09 | 6.1 | 1769 | 3721 | - | + | + | - | - | - | - | + |
WBC = white blood cell count, ALC = absolute lymphocyte count, ANC = absolute neutrophil count, ND = not done.