Table 1.

General characteristics of vaccinated and unvaccinated groups based on vaccination type

Vaccination type	Demographic/Characteristic		Vaccinated patients		Matched comparators		Prevalence ratio (95% CI)
			n	%	n	%
Zoster	All		854,745		8,490,813
	Gender	Male	407,361	47.7	4,046,215	47.7
		Female	447,384	52.3	4,444,598	52.3
	Age	70–74	519,822	60.8	5,177,036	61.0
		75–79	275,698	32.3	2,733,974	32.2
		80–84	58,401	6.8	572,024	6.7
		85–89	610	0.1	5,821	0.1
		90 +	214	0.03	1,958	0.02
	Ethnicity	White	702,463	82.2	6,636,714	78.2
		Asian	25,113	2.9	226,362	2.7
		Black	10,488	1.2	116,742	1.4
		Other	8,569	1.0	93,022	1.1
		Unknown	108,112	12.6	1,417,973	16.7
	IMD	1 (least deprived)	236,851	27.7	2,238,248	26.4
		2	205,189	24.0	2,000,088	23.6
		3	171,309	20.0	1,721,476	20.3
		4	137,555	16.1	1,412,409	16.6
		5 (most deprived)	103,292	12.1	1,112,569	13.1
		Unknown	549	0.1	6,023	0.1
	Baseline comorbidities:
		Any malignancy	193,171	22.6	1,905,820	22.4	1.01 (1.00, 1.01)
		Cerebrovascular disease	85,038	9.9	858,129	10.1	0.98 (0.98, 0.99)
		Chronic pulmonary disease	171,459	20.1	1,587,020	18.7	1.07 (1.07, 1.08)
		Congestive heart failure	44,400	5.2	454,834	5.4	0.97 (0.96, 0.98)
		Diabetes with chronic complications	103,028	12.1	909,926	10.7	1.12 (1.12, 1.13)
		Diabetes without chronic complications	161,741	18.9	1,443,053	17.0	1.11 (1.11, 1.12)
		AIDS/HIV	194	0.02	4,855	0.1	0.40 (0.34, 0.46)
		Hemiplegia or paraplegia	8,184	1.0	105,649	1.2	0.77 (0.75, 0.79)
		Metastatic solid tumour	14,187	1.7	195,887	2.3	0.72 (0.71, 0.73)
		Mild liver disease	14,457	1.7	160,340	1.9	0.90 (0.88, 0.91)
		Moderate or severe liver disease	5,505	0.6	65,993	0.8	0.83 (0.81, 0.85)
		Myocardial infarction	61,399	7.2	588,844	6.9	1.03 (1.03, 1.04)
		Peptic ulcer disease	59,548	7.0	571,816	6.7	1.03 (1.02, 1.04)
		Peripheral vascular disease	50,170	5.9	502,301	5.9	0.99 (0.98, 1.00)
		Renal disease	143,735	16.8	1,371,452	16.2	1.04 (1.03, 1.05)
		Rheumatic disease	55,879	6.5	653,749	7.7	0.85 (0.84, 0.86)
	Antiviral treatment history (at baseline)		90,344	10.6	845,499	10.0	1.06 (1.05, 1.07)
Influenza	All		742,487		7,219,770
	Gender	Male	344,460	46.4	3,351,283	46.4
		Female	398,027	53.6	3,868,487	53.6
	Age	70–74	307,303	41.4	3,071,413	42.5
		75–79	201,955	27.2	1,992,571	27.6
		80–84	130,963	17.6	1,271,165	17.6
		85–89	68,996	9.3	640,653	8.9
		90 +	33,270	4.5	243,968	3.4
	Ethnicity	White	607,439	81.8	5,468,741	75.7
		Asian	21,003	2.8	167,049	2.3
		Black	9,630	1.3	106,665	1.5
		Other	7,763	1.0	75,869	1.1
		Unknown	96,652	13.0	1,401,446	19.4
	IMD	1 (least deprived)	199,952	26.9	1,877,787	26.0
		2	172,867	23.3	1,664,335	23.1
		3	149,466	20.1	1,460,983	20.2
		4	122,125	16.4	1,204,077	16.7
		5 (most deprived)	97,481	13.1	1,005,699	13.9
		Unknown	596	0.1	6,889	0.1
	Baseline comorbidities:
		Any malignancy	201,889	27.2	1,730,019	24.0	1.13 (1.12, 1.13)
		Cerebrovascular disease	98,482	13.3	880,249	12.2	1.07 (1.06, 1.08)
		Chronic pulmonary disease	154,449	20.8	1,254,053	17.4	1.19 (1.19, 1.20)
		Congestive heart failure	57,757	7.8	485,843	6.7	1.13 (1.12, 1.14)
		Diabetes with chronic complications	91,204	12.3	742,247	10.3	1.19 (1.18, 1.20)
		Diabetes without chronic complications	141,673	19.1	1,176,490	16.3	1.17 (1.16, 1.17)
		AIDS/HIV	277	0.04	2,564	0.04	1.06 (0.93, 1.19)
		Hemiplegia or paraplegia	10,097	1.4	101,623	1.4	0.95 (0.93, 0.97)
		Metastatic solid tumour	17,522	2.4	160,371	2.2	1.06 (1.05, 1.08)
		Mild liver disease	15,922	2.1	142,440	2.0	1.09 (1.07, 1.11)
		Moderate or severe liver disease	5,612	0.8	49,966	0.7	1.10 (1.07, 1.13)
		Myocardial infarction	61,985	8.3	522,655	7.2	1.14 (1.13, 1.15)
		Peptic ulcer disease	55,733	7.5	487,815	6.8	1.10 (1.09, 1.11)
		Peripheral vascular disease	52,918	7.1	457,310	6.3	1.11 (1.10, 1.12)
		Renal disease	163,397	22.0	1,396,081	19.3	1.12 (1.11, 1.12)
		Rheumatic disease	63,273	8.5	540,088	7.5	1.13 (1.12, 1.14)
	Antiviral history (at baseline)		81,419	11.0	716,244	9.9	1.10 (1.10, 1.11)