Table 2.

Single nucleotide polymorphism analysis of 30 loci in 6 genes in chronic HBV-infected patients and healthy controls

Gene	dbSNPrs#	Position	dbSNPallele	Type	Chronic HBV-infected patients gene frequency (n = 1007)	Healthy controls gene frequency (n = 1040)	P value
AKR1C2	rs2801904	chr10:5041692	C > A	Intron	0.757	0.750	0.758
	rs12414884	chr10:5021206	T > G	Intron	0.189	0.136	0.200
AKR1C3	rs2096421	chr10:5055213	G > A	Intron	0.750	0.735	0.449
	rs2398203	chr10:5134591	C > T	Intron	0.189	0.184	0.777
	rs2186174	chr10:5134535	A > C	Intron	0.189	0.188	0.955
	rs2211623	chr10:5062949	G > C	Intron	0	0	–
	rs2154306	chr10:5101710	T > C	Intron	0	0	–
	rs4559587	chr10:5100663	C > A	Intron	0	0	–
	rs12529	chr10:5094459	C > G	Missense	0	0	–
	rs3763676	chr10:5094307	A > G	Intron	0	0	–
HSD17B6	rs4237805	chr12:56855861	G > A	Intron	0.156	0.140	0.350
	rs898611	chr12:56769532	C > A	Intron	0.802	0.799	0.868
SRD5A1	rs3797177	chr5:6666971	T > A	Intron	0.216	0.211	0.747
	rs248800	chr5:6660287	C > A	Intron	0.223	0.207	0.361
	rs1691053	chr5:6677052	T > C	Intron	0.220	0.027	0.417
	rs248799	chr5:6694579	G > A	Intron	0	0	–
	rs6872996	chr5:6661853	C > T	Intron	0	0	–
SRD5A2	rs2208532	chr2:31563919	G > A	Intron	0.405	0.384	0.320
	rs12470143	chr2:31538488	C > T	Intron	0.198	0.286	0.813
	rs523349	chr2:31580636	G > C	Missense	0.422	0.418	0.893
	rs4952197	chr2:31542061	A > G	Intron	0.564	0.544	0.374
	rs7594951	chr2:31566723	C > T	Intron	0.103	0.080	0.066
	rs612224	chr2:35186801	C > A	Intron	0.051	0.049	0.452
ESR1	rs6909023	chr6:151832562	G > A	Intron	0.137	0.096	0.974
	rs6920483	chr6:151810186	G > A	Intron	0.117	0.114	0.890
	rs2077647	chr6:151807942	T > C	Exonic	0.367	0.257	0.493
	rs2234693	chr6:151842200	T > C	Intron	0.385	0.368	0.438
	rs1062577	chr6:152102770	T > A	UTR3	0.310	0.306	0.848
	rs7753153	chr6:151826963	G > A	Intron	0.243	0.238	0.836
	rs9340799	chr6:151842246	A > G	Intron	0.204	0.198	0.783