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. 2023 Oct 3;14:68. doi: 10.1186/s13293-023-00553-4

Table 3.

Genotype and allele frequencies of two genetic variants in the SRD5A2 gene between male and female patients with chronic HBV infection

Variants Male, n (%) Female, n (%) χ2 P value

SRD5A2 rs12470143

Genotype

 CC 461 (69.4%) 294 (85.7%) 44.949  < 0.001
 CT 161 (24.2%) 24 (7.0%)
 TT 42 (6.3%) 25 (7.3%)
Allele
 C 1083 (81.6%) 611 (89.1%) 19.119  < 0.001
 T 245 (18.4%) 75 (10.9%)

SRD5A2 rs7594951

Genotype

 CC 538 (81.0%) 309 (85.7%) 33.186  < 0.001
 CT 90 (13.6%) 8 (6.7%)
 TT 36 (5.4%) 26 (7.6%)
Allele
 C 1166 (87.8%) 626 (91.3%) 5.497 0.019
 T 162 (12.2%) 60 (8.7%)