FIG. 1.

Effect of fluconazole. Each isolate was tested by the microdilution version of the M27-A method, and the reduction in growth is expressed as a percentage of the growth in the drug-free growth control well (y axis) versus fluconazole concentration (in micrograms per milliliter, x axis) for the isolates for which the MICs were low/low (thin lines), the isolates for which the MICs were low/high (thick lines), and the isolates for which the MICs were high/high (dotted lines). Results for tests in 0.165 M MOPS-buffered (pH 7) RPMI 1640 medium are presented. GC, growth control. Similar results were obtained if testing was performed in medium supplemented with glucose at 20 g/liter (data not shown).