Primary Assessment Method: Endometrial Cancer (Cohort 3) | |
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Number of patients screened | 14 |
Number of patients enrolled | 10 |
Number of patients evaluable for toxicity | 10 |
Number of patients evaluated for efficacy | 6 |
Evaluation method | RECIST 1.1 |
Response assessment, CR | 0 (0%) |
Response assessment, PR | 0 (0%) |
Response assessment, SD | 2 (33.3%) |
Response assessment, PD | 4 (66.7%) |
Median duration assessments | 8.9 weeks |
Duration of treatment | 8.9 weeks |
Outcome notes | Two patients did not complete 1 cycle; of these, 1patient did not complete 1 cycle due to clinical progression and 1 patient did not complete a cycle due to intercurrent illness (a cerebrovascular accident) after 2 of 4 weekly doses in cycle 1 thought not to be related to ONC201. Two patients had clinical progression and did not have follow-up imaging. |