Table 3.
Multivariate logistic model after initial SARS-CoV-2 vaccination.
| Univariate logistic | Multivariate logistic | |||||
|---|---|---|---|---|---|---|
| Characteristic | OR1 | 95% CI | P value | OR | 95% CI | P-value |
| Vaccine type (after two doses only) | ||||||
| Moderna | — | — | — | — | ||
| Pfizer | 0.54 | 0.31, 0.91 | .02 | 0.47 | 0.26, 0.86 | .02 |
| Diagnosis | .03 | .02 | ||||
| CLL | — | — | — | — | ||
| Other NHL | 2.39 | 1.14, 5.31 | .03 | 4.15 | 1.48, 13.4 | .01 |
| WM | 2.17 | 0.87, 5.91 | .11 | 2.43 | 0.73, 9.11 | .20 |
| Age | 1.01 | 0.98, 1.03 | .60 | |||
| Gender | ||||||
| Female | — | — | ||||
| Male | 0.83 | 0.49, 1.41 | .50 | |||
| Race | ||||||
| White | — | — | ||||
| Other | 1.17 | 0.58, 2.40 | .70 | |||
| Prior COVID infection (via PCR) | ||||||
| No | — | — | ||||
| Yes | 0.94 | 0.44, 2.06 | .90 | |||
| Prior COVID infection (via nucleocapsid-Ab) | ||||||
| No | — | — | ||||
| Yes | Inf | 0.00, Inf | NA | |||
| Not tested | 2.32 | 1.26, 4.36 | .008 | |||
| Prior/current cancer treatment | ||||||
| No | — | — | — | — | ||
| Yes | 0.28 | 0.16, 0.49 | <.001 | 0.68 | 0.20, 2.42 | .50 |
| BCL-2 inhibitor ever? | ||||||
| No | — | — | — | — | ||
| Yes | 0.43 | 0.19, 0.94 | .04 | 1.51 | 0.54, 4.26 | .40 |
| BTK inhibitor ever? | ||||||
| No | — | — | — | — | ||
| Yes | 0.27 | 0.15, 0.47 | <.001 | 0.51 | 0.17, 1.42 | .20 |
| CD20 mAb ever? | ||||||
| No | — | — | ||||
| Yes | 0.35 | 0.20, 0.58 | <.001 | |||
| Chemo and anti-CD20 ever? | ||||||
| No | — | — | — | — | ||
| Yes | 0.53 | 0.26, 1.04 | .07 | 0.70 | 0.26, 1.83 | .50 |
| CD20 mAb within 1 year of first vaccine dose? | <.001 | <.001 | ||||
| Never | — | — | — | — | ||
| Not within 1 year | 0.60 | 0.33, 1.09 | .10 | 0.83 | 0.30, 2.25 | .70 |
| Yes | 0.10 | 0.04, 0.25 | <.001 | 0.11 | 0.03, 0.38 | <.001 |
Abbreviation: OR, odds ratio.