Table 2.
Best responses according to the line of treatment.
| Response category, n (%) | All patients (n = 304)*; n (%) | First-line therapy, (n = 137); n (%) | Second-line, therapy (n = 117); n (%) | ≥ Third-line therapy, (n = 50); n (%) | P-value |
|---|---|---|---|---|---|
| Complete response (CR) | 11 (3.6) | 8 (5.8) | 3 (2.6) | 0 (0) | .004 |
| Partial response (PR) | 118 (38.8) | 67 (48.9) | 36 (30.8) | 15 (30.0) | |
| Stable disease (SD) | 78 (25.7) | 23 (16.8) | 37 (31.6) | 18 (36.0) | |
| Progressive disease (PD) | 97 (31.9)) | 39 (28.5) | 41 (35.0) | 17 (34.0) | |
| Objective response rarte (ORR) (CR + PR) | 129 (42.4) | 75 (54.7) | 39 (33.3) | 15 (30.0) | <.001 |
| Disease control rate (DCR = CR + PR + SD) | 207 (68.1) | 98 (71.5) | 77 (65.0%) | 33 (66.0) | .43 |
*Four patients given only one course due to side effects were not included in the response rate analysis.