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. 2023 Sep 25;5(10):e594–e610. doi: 10.1016/S2665-9913(23)00211-4

Table.

Prevalence and burden of DALYs and deaths due to rheumatoid arthritis in 2020, and changes from 1990 to 2020, by sex and region

Number of prevalent cases, 2020 Age-standardised prevalence rate
Number of deaths, 2020 Age-standardised death rate
Number of DALYs
Age-standardised DALY rate
Rate per 100 000, 2020 Percentage change, 1990–2020 Rate per 100 000, 2020 Percentage change, 1990–2020 Number, 2020 Percentage change, 1990–2020 Rate per 100 000, 2020 Percentage change, 1990–2020
Global 17 600 000 (15 800 000 to 20 300 000) 208·8 (186·8 to 241·1) 14·1% (12·7 to 15·4) 38 300 (33 500 to 44 000) 0·5 (0·4 to 0·5) −23·8% (−29·3 to −17·5) 3 060 000 (2 320 000 to 3 860 000) 96·2% (88·6 to 102·6) 36·4 (27·6 to 45·9) −1·0% (−5·5 to 2·2)
Males 4 870 000 (4 310 000 to 5 710 000) 119·8 (106·3 to 140·0) 17·2% (15·6 to 18·7) 12 400 (9200 to 14 300) 0·3 (0·3 to 0·4) −16·5% (−30·9 to −6·3) 894 000 (679 000 to 1 130 000) 106·7% (94·6 to 116·2) 22·3 (17·0 to 28·0) 2·4% (−4·7 to 8·0)
Females 12 700 000 (11 400 000 to 14 500 000) 293·5 (262·7 to 336·3) 13·6% (12·0 to 15·0) 25 900 (22 200 to 30 400) 0·6 (0·5 to 0·7) −25·9% (−32·3 to −18·5) 2 170 000 (1 650 000 to 2 740 000) 92·2% (84·2 to 99·5) 49·7 (37·6 to 63·0) −1·6% (−6·5 to 2·3)
Central Europe, eastern Europe, and central Asia 1 030 000 (914 000 to 1 180 000) 186·9 (162·8 to 215·7) 24·2% (21·7 to 26·7) 1900 (1770 to 2040) 0·3 (0·3 to 0·3) −19·1% (−25·0 to −12·6) 183 000 (139 000 to 228 000) 30·7% (24·8 to 35·8) 32·4 (24·2 to 40·9) 8·1% (2·7 to 12·5)
Central Asia 171 000 (149 000 to 197 000) 182·7 (160·0 to 208·0) 41·7% (36·9 to 47·6) 124 (112 to 139) 0·2 (0·2 to 0·2) 530·6% (388·9 to 714·0) 26 500 (19 100 to 34 500) 166·9% (146·6 to 187·7) 28·9 (21·1 to 37·3) 59·0% (48·4 to 71·5)
Central Europe 349 000 (313 000 to 397 000) 202·1 (177·6 to 232·9) 20·0% (17·7 to 22·7) 488 (434 to 533) 0·2 (0·2 to 0·2) −57·8% (−62·5 to −54·7) 56 100 (41 600 to 72 800) 12·0% (4·1 to 17·8) 31·7 (22·8 to 42·1) −8·5% (−16·6 to −2·4)
Eastern Europe 514 000 (450 000 to 588 000) 176·6 (152·3 to 204·0) 22·0% (19·1 to 25·3) 1290 (1190 to 1400) 0·4 (0·3 to 0·4) 6·4% (−2·4 to 18·2) 100 000 (78 000 to 123 000) 25·5% (21·0 to 30·5) 33·4 (25·5 to 41·3) 12·7% (8·1 to 17·1)
High income 4 920 000 (4 520 000 to 5 450 000) 288·1 (262·6 to 324·0) 11·3% (9·6 to 12·8) 9640 (8260 to 10 400) 0·4 (0·3 to 0·4) −43·8% (−47·4 to −40·9) 798 000 (602 000 to 992 000) 46·1% (40·3 to 49·8) 45·4 (33·5 to 57·6) −5·7% (−10·5 to −2·6)
Australasia 158 000 (143 000 to 178 000) 355·6 (318·1 to 406·9) 13·0% (7·2 to 18·4) 291 (251 to 322) 0·5 (0·5 to 0·6) −45·8% (−52·0 to −40·4) 25 400 (18 900 to 32 500) 83·6% (68·4 to 93·0) 55·9 (41·1 to 72·6) −5·7% (−13·9 to −0·7)
High-income Asia Pacific 910 000 (810 000 to 1 040 000) 266·9 (236·7 to 312·9) −8·1% (−11·1 to −5·1) 2420 (1940 to 2710) 0·4 (0·3 to 0·5) −53·7% (−58·4 to −50·9) 156 000 (118 000 to 196 000) 35·4% (29·6 to 39·3) 43·3 (31·4 to 56·4) −23·8% (−29·3 to −19·6)
High-income North America 1 620 000 (1 490 000 to 1 750 000) 300·5 (278·5 to 322·3) 18·2% (16·7 to 19·6) 2500 (2180 to 2700) 0·4 (0·3 to 0·4) −29·3% (−33·8 to −26·0) 254 000 (191 000 to 319 000) 72·5% (67·8 to 77·1) 46·3 (34·4 to 58·9) 4·3% (0·8 to 7·4)
Southern Latin America 210 000 (187 000 to 237 000) 266·1 (235·3 to 302·1) 62·0% (54·5 to 72·3) 416 (378 to 450) 0·5 (0·4 to 0·5) −11·1% (−19·1 to −2·3) 36 300 (26 900 to 46 000) 126·7% (108·9 to 140·5) 45·5 (33·5 to 58·0) 32·9% (22·5 to 41·9)
Western Europe 2 020 000 (1 840 000 to 2 290 000) 284·9 (252·4 to 328·7) 11·0% (9·3 to 12·5) 4010 (3490 to 4350) 0·4 (0·3 to 0·4) −49·9% (−53·6 to −46·6) 327 000 (245 000 to 410 000) 28·5% (22·0 to 33·4) 44·5 (32·4 to 57·2) −7·1% (−12·8 to −2·9)
Latin America and Caribbean 1 690 000 (1 500 000 to 1 930 000) 269·7 (238·8 to 306·6) 24·2% (21·2 to 26·5) 3560 (3210 to 3850) 0·6 (0·5 to 0·7) −28·2% (−34·3 to −23·4) 304 000 (229 000 to 384 000) 153·7% (144·0 to 164·4) 48·7 (37·0 to 61·4) 8·2% (3·6 to 12·6)
Andean Latin America 268 000 (241 000 to 301 000) 427·8 (385·9 to 479·2) 63·1% (54·8 to 70·6) 363 (307 to 417) 0·7 (0·6 to 0·8) −30·9% (−48·3 to −9·2) 42 200 (29 800 to 54 800) 227·0% (196·7 to 251·1) 68·2 (48·5 to 87·9) 34·5% (20·9 to 45·0)
Caribbean 79 800 (70 300 to 93 800) 153·4 (134·9 to 180·5) 32·3% (27·4 to 36·7) 250 (223 to 295) 0·5 (0·4 to 0·6) −15·1% (−27·0 to −2·0) 15 100 (11 500 to 19 400) 114·4% (97·3 to 128·2) 29·1 (22·0 to 37·3) 14·2% (5·8 to 21·9)
Central Latin America 915 000 (809 000 to 1 020 000) 357·2 (316·8 to 398·0) 23·8% (20·6 to 26·9) 2310 (2030 to 2560) 1·0 (0·9 to 1·1) −32·5% (−39·1 to −26·4) 173 000 (134 000 to 216 000) 170·0% (158·1 to 182·7) 68·2 (53·1 to 84·8) 3·5% (−2·2 to 9·1)
Tropical Latin America 430 000 (370 000 to 505 000) 169·0 (144·8 to 197·8) 0·8% (−2·0 to 3·9) 633 (567 to 678) 0·3 (0·2 to 0·3) −8·5% (−15·5 to −2·1) 73 300 (54 200 to 97 600) 105·6% (96·4 to 116·6) 28·9 (21·4 to 38·5) −1·3% (−4·9 to 4·1)
North Africa and Middle East 683 000 (599 000 to 797 000) 116·8 (104·2 to 134·6) 50·1% (46·3 to 54·6) 546 (462 to 686) 0·1 (0·1 to 0·2) −22·4% (−38·9 to 2·8) 107 000 (76 700 to 144 000) 216·1% (190·8 to 238·0) 18·8 (13·6 to 24·8) 27·8% (18·3 to 36·9)
South Asia 3 250 000 (2 850 000 to 3 820 000) 204·8 (181·7 to 238·1) 41·3% (37·8 to 44·5) 9930 (7490 to 14 300) 0·8 (0·6 to 1·2) −21·6% (−34·9 to −7·5) 614 000 (466 000 to 766 000) 180·7% (161·9 to 199·7) 40·6 (31·2 to 49·6) 10·2% (0·4 to 20·1)
Southeast Asia, east Asia, and Oceania 5 360 000 (4 750 000 to 6 280 000) 195·2 (171·4 to 228·9) 15·4% (12·5 to 18·0) 12 300 (10 200 to 14 800) 0·5 (0·4 to 0·6) −8·7% (−30·3 to 13·6) 959 000 (730 000 to 1 230 000) 109·3% (91·9 to 127·4) 35·2 (26·7 to 44·7) 1·1% (−8·3 to 9·1)
East Asia 4 830 000 (4 290 000 to 5 630 000) 238·4 (208·8 to 279·4) 16·6% (13·2 to 19·5) 11 300 (9320 to 13 600) 0·6 (0·5 to 0·7) −11·7% (−33·9 to 11·3) 866 000 (660 000 to 1 110 000) 105·4% (86·9 to 123·5) 42·6 (32·4 to 54·4) 1·5% (−9·3 to 9·8)
Oceania 5460 (4470 to 6710) 50·5 (42·1 to 60·7) 18·0% (13·8 to 22·4) 0·101 (0·0477 to 0·248) 0·0 (0·0 to 0·0) −12·2% (−39·6 to 35·5) 774 (511 to 1 120) 175·7% (155·8 to 204·5) 7·1 (4·8 to 10·1) 16·2% (7·4 to 27·6)
Southeast Asia 525 000 (446 000 to 638 000) 74·9 (64·2 to 90·2) 34·8% (31·1 to 39·0) 1030 (746 to 1190) 0·2 (0·1 to 0·2) −5·2% (−23·2 to 10·3) 92 700 (66 200 to 118 000) 154·1% (135·4 to 173·4) 13·8 (10·1 to 17·3) 17·1% (7·2 to 24·7)
Sub-Saharan Africa 641 000 (538 000 to 765 000) 96·3 (83·8 to 113·2) 3·8% (2·0 to 5·4) 446 (378 to 930) 0·1 (0·1 to 0·2) −31·6% (−45·4 to −7·5) 98 700 (68 100 to 131 000) 120·4% (109·3 to 130·7) 15·2 (10·9 to 19·5) −5·8% (−10·8 to −0·5)
Central Sub-Saharan Africa 78 900 (66 300 to 93 100) 103·5 (89·9 to 118·3) 19·4% (15·3 to 23·4) 19·6 (5·64 to 205) 0·0 (0·0 to 0·5) −31·4% (−61·3 to −17·6) 11 100 (7 420 to 16 300) 189·7% (159·2 to 221·6) 14·6 (10·0 to 23·2) 13·5% (0·6 to 26·8)
Eastern Sub-Saharan Africa 197 000 (164 000 to 236 000) 85·5 (74·6 to 98·9) 11·7% (9·6 to 13·3) 35·5 (12·6 to 381) 0·0 (0·0 to 0·3) −38·0% (−58·7 to −26·3) 28 000 (17 800 to 39 800) 156·8% (133·3 to 169·3) 12·0 (8·0 to 17·0) 7·6% (−0·6 to 12·4)
Southern Sub-Saharan Africa 188 000 (163 000 to 215 000) 260·5 (227·9 to 296·1) −10·0% (−12·2 to −8·2) 379 (327 to 429) 0·7 (0·6 to 0·8) −23·1% (−38·0 to 7·2) 34 800 (26 500 to 43 500) 58·5% (47·4 to 72·8) 50·5 (39·0 to 61·9) −18·8% (−24·5 to −9·9)
Western Sub-Saharan Africa 177 000 (144 000 to 220 000) 61·3 (51·6 to 75·1) 25·9% (22·5 to 29·4) 12·6 (6·24 to 21·1) 0·0 (0·0 to 0·0) 19·4% (−21·1 to 101·6) 24 700 (16 000 to 35 100) 207·1% (196·3 to 222·4) 8·5 (5·7 to 11·9) 24·3% (19·9 to 29·8)

Values in parentheses are 95% uncertainty intervals. Super-region and region numbers do not sum to the global prevalence due to rounding and modelling adjustments for nations with populations below 50 000. DALY=disability-adjusted life-year.