. Author manuscript; available in PMC: 2024 Sep 1.

Published in final edited form as: Ann Rheum Dis. 2023 May 5;82(9):1181–1190. doi: 10.1136/ard-2022-223105

Table 3.

STRING Interactome Analysis

Category	Term description	FDR	Antigens
TISSUES	Leukemia cell	0.00097	GAPDH, *TPI1, GMNN, CRBN, DDB2, SMAD2, PML, CBX3, PDPK1, HNRNPAB, MAPRE1, NFU1*
KEGG	Ubiquitin mediated proteolysis	0.002	RBX1, DDB2, ERCC8, *PML, DDB1*
Reactome	Post-translational protein modification	0.0095	USP18, RBX1, LMAN1, DDB2, SMAD2, ERCC8, *PML, DDB1, ARFGAP1, NUP50, FUT8, SEC23IP, MCFD2*
UniProt Keywords	Ubiquitin conjugation	0.0256	*RPAP3, GAPDH, TPI1, CRBN, DDB2, SMAD2, PML, DDB1, CBX3, PDPK1, NUP50, HNRNPAB, ZBTB46, ZNF655, SKIL*
UniProt Keywords	Antiviral defense	0.0394	POLR3B, *PML, POLR3H, ISG15*
WikiPathways	TGF-beta signaling pathway	0.0451	RBX1, SMAD2, *PML, SKIL*

Novel specificities are indicated in bold italics. Only pathways including at least two novel specificities are shown.