TABLE 3.

Survival (in days) of groups of 10 mice infected with 7.3 × 10⁵ CFU of C. albicans per mouse and treated from day 1 through 10 with amphotericin B or KY-62^a

Group	Mean	SEM
Control	7.4	1.5
Amphotericin B, 1 mg/kg i.v.	28.1b	2.9
Amphotericin B, 5 mg/kg i.p.	31b	0.0
KY-62, 1 mg/kg i.p.	28.7b	1.6
KY-62, 5 mg/kg i.p.	28.3b	2.7
KY-62, 10 mg/kg i.p.	31b	0.0
KY-62, 20 mg/kg i.p.	31b	0.0
KY-62, 30 mg/kg i.p.	31b	0.0

^aObservation was continued through day 30 after infection. 

^bSignificant prolongation of survival compared with controls.