Figure 1.

Measurement of choroidal thickness, choroidal vascularity, and drusen parameters. (A) Representative spectral-domain OCT B-scan image from a normal rhesus macaque eye and corresponding (B) binarized image performed using Niblack autolocal threshold with an overlay (yellow outline) of the binarized segment of the choroid within the subfoveal region of interest used to measure CT and CVI. (C) Representative color fundus photograph and (D) drusen map generated from the 20° × 20° OCT volume scan where (E) horizontal OCT B-scans were semiautomatically segmented to determine the RPE (orange line) and Bruch's membrane (white line) and each druse manually annotated to measure drusen number, average height, and volume. Scale bars: 200 µm.