Table 1.
Average Annual Percentage Change (AAPC) in IBD Hospitalization rates (all-cause, IBD-related, and non-IBD-related hospitalizations) from FY 2002 to 2018 with 95% confidence intervals (CI) stratified by disease type, age group, sex, and metropolitan status.a
| Stratification variable |
Diagnosis Type | |||||
|---|---|---|---|---|---|---|
| All-Cause | IBD-related | Non-IBD-related | ||||
| AAPC (95% CI) Relative to IBD Prevalent Population | AAPC (95% CI) Relative to General Population | AAPC (95% CI) Relative to IBD Prevalent Population | AAPC (95% CI) Relative to General Population | AAPC (95% CI) Relative to IBD Prevalent Population | AAPC (95% CI) Relative to General Population | |
| IBD | −4.18 (−4.69, −3.66) | 1.56 (1.32, 1.80) | −5.54 (−6.19, −4.88) | −0.27 (−0.53, −0.01) | −1.82 (−2.14, −1.49) | 4.15 (3.48, 4.81) |
| CD | −4.06 (−4.56, −3.55) | 0.42 (0.11, 0.72)b | −5.07 (−5.69, −4.44) | −1.08 (−1.43, −0.73)b | −2.16 (−2.71, −1.60)b | 2.87 (2.30, 3.44)b |
| UC | −3.66 (−4.38, −2.93) | 3.29 (2.94, 3.63)b | −5.37 (−6.28, −4.46) | 1.24 (0.75, 1.73)b | −0.50 (−1.05, −0.06)b | 5.98 (5.11, 6.86)b |
| <18 | −5.46 (−6.67, −4.23) | −3.21 (−4.40, −2.01) | −6.02 (−7.19, −4.85) | −3.77 (−4.97, −2.57) | −2.79 (−4.75, −0.80) | −0.53 (−2.51, 1.48) |
| 18-39 | −4.97 (−5.60, −4.33) | −2.12 (−2.48, −1.76) | −6.24 (−6.98, −5.50) | −3.36 (−3.80, −2.92) | −2.11 (−2.59, −1.63) | 0.47 (−0.09, 1.03) |
| 40-59 | −3.41 (−3.84, −2.97)c | 1.17 (0.76, 1.59)c | −4.89 (−5.41, −4.37) | −0.35 (−0.76, 0.06)c | −0.70 (−1.13, −0.27) | 3.86 (3.14, 4.59)c |
| 60-79 | −3.33 (−3.82, −2.84)c | 3.44 (2.97, 3.91)c | −4.53 (−5.36, −3.69)d | 2.28 (1.69, 2.89)c | −2.18 (−2.59, −1.77) | 4.50 (3.81, 5.20)c |
| 80+ | −2.77 (−3.61, −1.92)c | 6.60 (5.59, 7.63)c | −4.99 (−6.33, −3.63) | 4.44 (3.40, 5.48)c | −1.33 (−2.18, −0.47) | 8.22 (6.70, 9.75)c |
| Female | −4.07 (−4.63, −3.50) | 1.66 (1.33, 1.99) | −5.70 (−6.45, −4.95) | −0.39 (−0.66, −0.12) | −1.58 (−1.99, −1.16) | 4.34 (3.57, 5.12) |
| Male | −4.28 (−4.84, −3.72) | 1.43 (1.13, 1.73) | −5.36 (−6.06, −4.65) | −0.13 (−0.50, −0.24) | −2.12 (−2.57, −1.67) | 3.82 (3.13, 4.51) |
| Metropolitan | −3.36 (−3.82, −2.90)e | 2.35 (2.09, 2.61)e | −4.67 (−5.19, −4.14)e | −0.56 (−0.25, −0.86)e | −1.04 (−1.51, −0.57)e | 4.92 (4.37, 5.47)e |
| Nonmetropolitan | −5.47 (−6.20, −4.75)e | 0.27 (−0.05, 0.59)e | −6.96 (−8.00, −5.92)e | −1.66 (−2.02, −1.29)e | −3.04 (−3.49, −2.59)e | 2.86 (1.92, 3.81)e |
aAAPCs are calculated using both the IBD-specific prevalent population (all IBD, CD, or UC) and the total Alberta population denominators, respectively. (Green, significantly decreasing; red, significantly increasing; yellow, stable).
bAAPC trends comparing UC to CD show a significant effect measure modifier (P < .001).
cAAPC trends comparing age group to the referent age group (<18) show a significant effect measure modifier (P < .001).
dAAPC trends comparing age group to the referent age group (<18) show a significant effect measure modifier (p=0.04).
eAAPC trends comparing Metropolitan to Non-metropolitan show a significant effect measure modifier (P < .001).