Table 3:
Intradialytic variables related to RCA during PIKRT.
| Variable | SLED start | SLED 2 h | SLED 4 h | SLED 6 h | SLED 8 h | ANOVA | P |
|---|---|---|---|---|---|---|---|
| ACT, s | 115.6 (13.5) | 118.0 (13.1) | 117.1 (12.1) | 116.5 (15.0) | 119.2 (15.9) | F(2.94, 70.65) = 0.991 | .401 |
| s-Ca2+, mmol/L | 1.13 (0.09) | 1.14 (0.07) | 1.16 (0.08)** | 1.20 (0.05)*,***,**** | 1.20 (0.06) | F(1.77, 42.49) = 8.823 | <.001 |
| c-Ca2+, mmol/L | NA | 0.40 (0.04) | NA | NA | NA | NA | NA |
| CaCl2, mL/h | 11.1 (0.5) | 11.7 (1.4) | 11.9 (2.2) | 11.5 (2.2) | 11.4 (2.1) | F(1.49, 35.67) = 2.207 | .137 |
| HCO3−, mmol/L | 21.9 (2.2) | 21.3 (1.8) | 21.6 (1.8) | 21.5 (1.6) | 21.4 (1.8) | F(1.70, 40.88) = 1.826 | .178 |
| Lactate, mmol/L | 1.19 (0.64) | 1.27 (0.50 | NA | NA | NA | NA | .177 |
| Citrate, mmol/L | 0.58 ± 0.19 | NA | 0.70* ± 0.23 | 0.72* ± 0.27 | 0.74* ± 0.22 | F(3, 57) = 18.42 | <.001 |
*P < .01 in comparison with baseline; **P < .05 in comparison with 2 h; ***P < .01 in comparison with 2 h; ****P < .05 in comparison with 4 h.
Data are presented as mean (SD). Values are intended as measured on patients’ blood if not otherwise indicated. P-values refer to test for trend across all the available sample times.
ACT, activated clotting time; s-Ca2+, systemic ionized calcium; c-Ca2+, circuit ionized calcium; CaCl2, calcium chloride infusion; HCO3−, bicarbonate; NA, not available.