Table 2.
Multiple Cox Proportional Hazards Regression Analysis for Incident Hypertension of Tertiles of TyG and Modified TyG Indices
| Hazard ratio with 95% CI | ||||||||
|---|---|---|---|---|---|---|---|---|
| Men | Women | |||||||
| T1 | T2 | T3 | P value | T1 | T2 | T3 | P value | |
| TyG | ||||||||
| Unadjusted | 1 | 1.19 (1.00–1.42) | 1.42 (1.21–1.68) | <0.001 | 1 | 1.37 (1.18–1.59) | 2.07 (1.78–2.41) | <0.001 |
| Model 1 | 1 | 1.21 (1.02–1.44) | 1.49 (1.27–1.76) | <0.001 | 1 | 1.13 (0.97–1.32) | 1.61 (1.38–1.88) | <0.001 |
| Model 2 | 1 | 1.09 (0.92–1.30) | 1.20 (1.01–1.43) | 0.103 | 1 | 1.06 (0.91–1.24) | 1.36 (1.16–1.60) | <0.001 |
| Model 3 | 1 | 1.08 (0.91–1.30) | 1.16 (0.95–1.40) | 0.324 | 1 | 1.07 (0.91–1.25) | 1.37 (1.13–1.66) | 0.003 |
| TyG‐BMI | ||||||||
| Unadjusted | 1 | 1.29 (1.10–1.52) | 1.69 (1.45–1.97) | <0.001 | 1 | 1.47 (1.25–1.73) | 2.34 (2.00–2.74) | <0.001 |
| Model 1 | 1 | 1.37 (1.16–1.61) | 1.89 (1.61–2.21) | <0.001 | 1 | 1.38 (1.18–1.63) | 2.08 (1.78–2.43) | <0.001 |
| Model 2 | 1 | 1.10 (0.90–1.33) | 1.20 (0.92–1.57) | 0.416 | 1 | 1.25 (1.03–1.52) | 1.61 (1.23–2.10) | 0.002 |
| Model 3 | 1 | 1.06 (0.86–1.30) | 1.11 (0.84–1.48) | 0.759 | 1 | 1.23 (1.01–1.50) | 1.55 (1.16–2.06) | 0.011 |
| TyG‐waist circumference | ||||||||
| Unadjusted | 1 | 1.41 (1.16–1.70) | 2.16 (1.81–2.59) | <0.001 | 1 | 1.83 (1.57–2.14) | 2.83 (2.43–3.30) | <0.001 |
| Model 1 | 1 | 1.46 (1.20–1.76) | 2.27 (1.89–2.71) | <0.001 | 1 | 1.48 (1.27–1.74) | 2.03 (1.73–2.38) | <0.001 |
| Model 2 | 1 | 1.28 (1.04–1.57) | 1.76 (1.39–2.22) | <0.001 | 1 | 1.26 (1.06–1.49) | 1.49 (1.21–1.84) | <0.001 |
| Model 3 | 1 | 1.29 (1.04–1.59) | 1.77 (1.38–2.27) | <0.001 | 1 | 1.23 (1.03–1.47) | 1.43 (1.15–1.79) | 0.006 |
| TyG‐waist‐to‐height ratio | ||||||||
| Unadjusted | 1 | 1.48 (1.26–1.74) | 2.17 (1.85–2.54) | <0.001 | 1 | 2.21 (1.85–2.65) | 3.34 (2.82–3.96) | <0.001 |
| Model 1 | 1 | 1.50 (1.27–1.76) | 2.18 (1.86–2.56) | <0.001 | 1 | 1.80 (1.49–2.16) | 2.27 (1.90–2.72) | <0.001 |
| Model 2 | 1 | 1.30 (1.09–1.56) | 1.69 (1.36–2.10) | <0.001 | 1 | 1.54 (1.27–1.87) | 1.69 (1.35–2.11) | <0.001 |
| Model 3 | 1 | 1.31 (1.08–1.58) | 1.68 (1.33–2.13) | <0.001 | 1 | 1.53 (1.25–1.86) | 1.64 (1.30–2.07) | <0.001 |
BMI indicates body mass index; and TyG, triglyceride and glucose index. Significance was set at P<0.05. Model 1: adjusted for age. Model 2: adjusted for variables used in Model 1 plus BMI, physical activity, smoking status, and current drinker. Model 3: adjusted for variables used in Model 2 plus total cholesterol, high‐density lipoprotein cholesterol, fasting plasma glucose, C‐reactive protein, antidiabetes drugs, and antidyslipidemic drugs.