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. 2023 Oct 3;12:RP88189. doi: 10.7554/eLife.88189

Table 2. Categories included in single-nucleotide polymorphism (SNP) queries.

These terms were considered as glycemia related and are categorized as such on the Common Metabolic Diseases Knowledge portal, which was queried for the relevant SNPs. Also included but not listed here were variations of these terms that were adjusted for body mass index (BMI).

Fasting hormones Glucose related Tolerance test Diabetes risk
Insulin Fasting glucose 2 hr glucose T1D
Proinsulin Random glucose 2 hr insulin T2D
C-peptide Hba1c 2 hr C-peptide
Fasting glc–BMI interaction Acute insulin response
Fasting ins–BMI interaction SI-adjusted acute ins. Resp.
Gestational diabetes/altered fast glucose in pregnancy AUC insulin
AUC insulin/AUC glucose
Corrected insulin response
HOMA-B
HOMA-IR
Ins. Secretion rate
Ins. Sensitivity
Incremental ins. @ 30 min OGTT
Insulin @ 30 min OGTT
Peak ins. response
Peak ins. Response adj SI