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. 2023 Aug 25;46(9):1574–1586. doi: 10.2337/dci23-0030

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© 2023 by the American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/journals/pages/license.

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The timeline of the major therapeutic outcome trials focused on delaying DKD in patients with type 2 diabetes and CKD following the publication of RENAAL and IDNT (73–79). MoAs, mechanisms of action.