TABLE 2.
Values of kinetic parameters for SST-K, SRT-1, and SST-1
Substrate | SST-K
|
SRT-1
|
SST-1
|
||||
---|---|---|---|---|---|---|---|
Km (μM) | Relative Vmaxa | Km (μM) | Relative Vmaxa | Km (μM) | Ki (μM) | Relative Vmaxa | |
Cephaloridine | 670 | 100 | 660 | 100 | 180 | —b | 100 |
Cefuroxime | 370 | 340 | 330 | 350 | — | 0.3 | <1 |
Cefotaxime | 390 | 400 | 410 | 410 | — | 2.8 | <1 |
Cefmenoxime | 180 | 120 | 170 | 130 | — | 1.7 | <1 |
Ceftazidime | 180 | 20 | 150 | 20 | — | 120 | <1 |
Values relative to that for cephaloridine, which was set at 100.
—, not tested.