Fig. 5. Retrosynthesis planning for protokylol has been carried out by RetroExplainer.

A four-step synthetic route to protokylol is presented. In each step, the portion of the text in blue highlights the documented evidence supporting the reaction, whereas the red section describes the decision-making process of our model. Key abbreviations include: DCC for N,N’-Dicyclohexylcarbodiimide; NHS for N-Hydroxysuccinimide; DCM for Dichloromethane; BMS for Dimethyl sulfide borane; THF for Tetrahydrofuran; STAB for Sodium triacetoxyborohydride; RT for Room Temperature; and $\mathrm{\Delta }E$ represents the change in energy scores value.