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. 2022 Nov 11;13(10):4318–4336. doi: 10.1016/j.apsb.2022.11.006

Figure 2.

Figure 2

PLG had good biocompatibility and the loading of DFO further increased its biological activity (A) Hemolysis rate of Lap, PRP and PLG. The inset is the supernatant imaging of RBCs in different treatment groups (n = 3). Cell viability of (B) HUVEC and (C) L929 treated with the release media of PLG or PG with different leaching concentrations (n = 5). (D) Live/dead staining of fibroblasts (green fluorescence, Calcein-AM indicates live cells; red fluorescence: propidium iodide indicates dead cells). (E) Cell proliferation rate of L929 by MTT (n = 5). (F) Representative optical images showing the HUVEC cells migrations in scratch assay. (G) Quantitative analysis of wound closure rate in scratch assay (n = 3). (H) Effects of various hydrogels on the tube formation of HUVEC. (I) Quantification of tube junctions and meshes in tube formation assay (n = 3). Data are reported as mean ± SD. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001. ns, not significant.