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. 2023 Sep 20;14:1228857. doi: 10.3389/fmicb.2023.1228857

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Copyright © 2023 Zhang, Xiao, Zhang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Feeding recombinant L. plantarum can prevent the combined infection of F. nucleatum and DSS. (A) Combined infection of F. nucleatum and DSS. F. nucleatum co-infection with DSS on days 5 and 7. a: PBS b: NC8 c: NC8-pSIP409-pgsA'-FomA. d: NC8-pSIP409-FnBPA-pgsA'-FomA. (B) Statistics of body weight loss rate in mice. (C) Statistics of the mouse survival curves. (D) Statistics of the colon length in mice. (E) Pathological sections of the mouse colon are displayed. a: PBS b: NC8 c: NC8-pSIP409-pgsA'-FomA. d: NC8-pSIP409-FnBPA-pgsA'-FomA. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001.