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. 2023 Sep 20;14:1268900. doi: 10.3389/fimmu.2023.1268900

Figure 6.

Figure 6

Anti-hTIGIT Nbs show high signal-to-noise ratios compared to the control Nb R3B23 and the scFv Vibo. Ratios of uptake of 99mTc-labeled anti-hTIGIT Nbs in TC-1 hTIGIT+ tumor to (A) TC-1 WT tumor, (B) muscle, (C) blood or to (D) liver (n=3), ratios are calculated as following: uptake in TC-1 hTIGIT+ divided by uptake in TC-1 WT tumor, muscle, liver, or blood. One-way ANOVA was used to evaluate statistical significance. Statistical significance was set at p<0.05 and only shown for significant data (*=p<0.05, **=p<0.01, ****=p<0.0001).