Figure 1. Selection of Randomized Trials Evaluating the Effect of the Use of CPAP on Major Cardiovascular and Cerebrovascular Adverse Events.

CPAP indicates continuous positive airway pressure; EU, European Union; ISAACC, Impact of Sleep Apnea Syndrome in the Evolution of Acute Coronary Syndrome⁷; OSA, obstructive sleep apnea; RICCADSA, Randomized Intervention With CPAP in Coronary Artery Disease and Sleep Apnea⁸; and SAVE, Sleep Apnea cardioVascular Endpoints.⁶