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. Author manuscript; available in PMC: 2023 Oct 4.
Published in final edited form as: Clin Gastroenterol Hepatol. 2022 Apr 6;20(8):1663–1667.e1. doi: 10.1016/j.cgh.2022.03.002

Table 1.

High-Risk and Worrisome Features in Pancreatic Cysts

High-risk Worrisome

Jaundice secondary to the cyst Acute pancreatitis
Cytology with high-grade dysplasia or cancer Mural nodule <5 mm, thickened/enhancing cyst walls
Pancreatic duct of ≥10 mm Main duct size 5–9 mm
5-mm mural nodule or solid mass Abrupt change in caliber of pancreatic duct
Increased serum level of CA19–9
Rapid cyst growth
Cyst size >37 or 4 cm4

Modified from Tanaka M, Fernandez-Del Castillo C, Kamisawa T, et al. Revisions of International Consensus Fukuoka Guidelines for the management of IPMN of the pancreas. Pancreatology 2017;17:738–753.

NOTE. The International Association of Pancreatology, American Gastrointestinal Association, American College of Gastroenterology, American College of Radiology, and European guidelines use different size cutoffs.