Table 4.

CCR5 Radioligand Binding Affinity^a

compounds	Ki (nM)b
VZMC013	3.29 ± 0.29
VZMC017	5.70 ± 0.23
VZMC019	NDc
VZMC001	239 ± 56d
MIP-1β	0.056 ± 0.006

^a[¹²⁵I]MIP-1α was used as the radioligand in the binding assay.

^bK_i values were calculated using the Cheng–Prusoff equation. The values are the mean ± SEM of at least three independent experiments.

^cIts IC₅₀ value is higher than 10,000 nM, the highest concentration tested.

^dData have been reported in ref 33 and are presented here for comparisons. It should be noted that the assay methods employed in both studies are similar to minor differences.