Table 4.
Agreement of individual observer visual Test Line scoring and the visual Test Line consensus score with numerical ESEQuant LF Reader measurements
| Observer identifier | No. RDTs read | Agreement between individual and consensus visual Test Line scoring and ESEQuant result ranges | |||||
|---|---|---|---|---|---|---|---|
| Analysis using five ESEQuant result ranges; 0–4 | Analysis using three ESEQuant result ranges; negative, weakly reactive, and positive | ||||||
| Percentage agreement | Kappa value | 95% CI: kappa value | Percentage agreement | Kappa value | 95% CI: kappa value | ||
| A | 91 | 79.1 | 0.70 | 0.64–0.77 | 96.70 | 0.93 | 0.83–1.00 |
| B | 65 | 83.1 | 0.76 | 0.68–0.83 | 96.92 | 0.94 | 0.82–1.00 |
| C | 95 | 82.1 | 0.75 | 0.69–0.81 | 96.84 | 0.94 | 0.84–1.00 |
| D | 30 | 80.0 | 0.69 | 0.57–0.81 | 93.33 | 0.88 | 0.71–1.00 |
| E | 10 | 80.0 | 0.44 | 0.3–0.58 | 100.00 | 1.00 | 0.68–1.00 |
| F | 84 | 86.9 | 0.81 | 0.75–0.88 | 96.43 | 0.93 | 0.83–1.00 |
| Test Line consensus | 125 | 88.8 | 0.84 | 0.78–0.89 | 97.60 | 0.95 | 0.87–1.00 |
| Observer average | 81.9 | 0.69 | 96.7 | 0.93 | |||
Each of the six staff members performing visual RDT interpretations was pseudonymized for publication and designated as A–F. No., number; RDT, rapid diagnostic test; 95% CI, 95% confidence interval.