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. 2023 Oct 4;23:712. doi: 10.1186/s12903-023-03357-5

Table 2.

Randomized trials reporting treatment of gingival recession

Author (year) Study Design, Blinded (duration) Population Intervention (number of surgical sites)
No. of participants (sites) Age (mean/range) gender Control (sites) Test (sites)
Bozkurt et al. (2015) [29] Split-mouth, examiner-blinded (6 months) 20 (119) 37.1 ± 1.03 (20–45) 7 M/13F CAF (59) CAF + CGF (60)
Akcan et al. (2020) [55] Split-mouth, N (6 months) 19 (74) N (20–63) 11 M/8F CAF + CTG (37) CAF + CGF (37)
Korkmaz et al. (2021) [59] Parallel, examiner-blinded (6 months) 40 (108) 41.1 ± 9.3 (26–63) N TT + CTG (51) TT + CGF (57)
Xue et al. (2022) [67] Parallel, N (6 months) 28 (70) 38.56 ± 9.28 (N) 17 M/11F CAT + CTG (34) CAT + CGF (36)
Öngöz et al. (2023) [46] Parallel, examiner-blinded (6 months) 16 (45) 35.31 ± 5.55 (25–45) 8 M/8F CAF (15) T1: CAF + CGF (15); T2: CAF + PRF (15)

CAF: coronally advanced flap; CTG: connective tissue graft; CGF: concentrated growth factor; TT: tunnel technique; N: not mentioned