Table 3.

Estimation of sensitivity, specificity, and positive and negative predictive values of diagnostic methods used in this study to detect Plasmodium spp. using microscopy as reference

	RDT	Field-cLAMP	Lab-cLAMP	Lab-qLAMP
Sensitivity (95% CI)	92.5% (86.2%, 98.8%)	98.5% (95.6%, 101.4%)	89.6% (82.2%, 96.9%)	86.6% (78.4%, 94.7%)
Specificity (95% CI)	72.9% (65.4%, 80.5%)	65.4% (57.3%, 73.5%)	76.7% (69.5%, 83.9%)	78.9% (72.0%, 85.9%)
PPV (95% CI)	63.3% (53.7%, 72.8%)	58.9% (49.8%, 68.0%)	65.9% (56.2%, 75.7%)	67.4% (57.5%, 77.3%)
NPV (95% CI)	95.1% (90.9%, 99.3%)	98.9% (96.6%, 101.1%)	93.6% (89.0%, 98.2%)	92.1% (87.2%, 97.1%)

RDT, Rapid Diagnostic Tests; Field-cLAMP, colorimetric field LAMP assay; Lab-cLAMP, colorimetric laboratory LAMP assay; Lab-qLAMP, laboratory real-time LAMP assay; PPV, positive predictive value; NPV, negative predictive value; CI, confidence intervals