Figure 4.
(A) In vivo MR imaging of tumor-bearing mice after injection of IR780@BSA@SPIO nanosystem. Color according to the local gray value. (B) NIR-II fluorescence imaging of tumor-bearing mice administrated with various drugs and isolated organs and tumors after 72 h (H: heart; Li: liver; S: spleen; L: lung; K: kidney; T: tumor). Semi-quantitative analysis of fluorescence intensity from tumor-bearing mice (C) and isolated organs and tumors (D). The data are expressed as mean ± standard deviation (n = 3). Signal intensity differences between BSA-based nanosystems and free IR780 group were analyzed, *P < 0.05.