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. 2023 Sep 20;13:1266868. doi: 10.3389/fonc.2023.1266868

Table 1.

Disease and clinical characteristics of the 145 NDMM patients.

Variables All patients (N=145)
Male (N, %) 84(57.9%)
Age 58(31, 73)
ISS stage (N, %)
 stage I
 stage II
 stage III

26(17.9%)
63(43.4%)
56(38.6%)
R-ISS stage (N, %)
 stage I
 stage II
 stage III

21(14.5%)
97(66.9%)
27(18.6%)
Hemoglobin (g/L) 90.9 ± 24.8
Platelets (×109/L) 171.2 ± 66.5
Albumin (g/L) 33.6 ± 6.9
Globulin (g/L) 44.5(12.5, 125.8)
Lactate ehydrogenase (LDH) (U/L) 157.6(59.9, 611.9)
Creatinine clearance rate (CCR)
ml/(min×1.73m2)
 <40
 ≥40

47(32.4%)
98(67.6%)
Calcium (mmol/L) 2.2(1.8, 3.6)
β2-microglobulin (mg/L) 4.0(0.86, 64.2)
Circulating plasma cells (cPCs,≥0.165%)
 Positive
 Negative

99(68.2%)
46(33.8%)
M-protein (g/L) 20.4(0.21, 104.5)
Bone marrow plasma cell (BMPC) (%) 28.0(10.0, 95.5%)
FISH (N,%)
 High risk
 Standard risk

36(24.8%)
109(75.2%)
Autologous stem cell transplantation (ASCT)
(N, %)
Yes
No

107(73.8%)
38(26.2%)