Table 3.

Univariable and Multivariable analysis of factors predicting PFS and OS in NDMM patients.

Variable	PFS				OS
	Univariable		Multivariable		Univariable		Multivariable
	p	HR (95%CI)	p	HR (95%CI)	p	HR (95%CI)	p	HR (95%CI)
Age (≥65)	0.188	1.687 (0.774, 3.674)	–	–	0.131	2.307 (0.780, 6.825)	0.146	2.652 (0.711, 9.893)–
ISS stage II/III	0.049	7.387 (1.008, 54.1125)	0.125	4.946 (0.642, 38.096)	0.266	–	–	–
CCR ≥40	0.056	1.979 (0.981, 3.989)	0.407	0.715 (0.323, 1.580)	0.117	–	–	–
High risk	0.025	2.246 (1.109, 4.551)	0.434	1.331 (0.651, 2.721)	0.042	2.877 (1.041, 7.951)	0.738	1.210 (0.397, 3.682)
LDH	<0.001	1.005 (1.002, 1.008)	0.001	1.005 (1.002, 1.007)	<0.001	1.008 (1.004, 1.011)	<0.001	1.008 (1.004, 10.13)
cPCs ≥0.165%	0.001	3.040 (1.512, 6.111)	0.041	2.118 (1.032, 4.349)	0.003	4.319 (1.532, 12.176)	0.036	3.315 (1.079, 10.182)
ASCT	<0.001	0.216 (0.106, 0.440)	<0.001	0.209 (0.091, 0.448)	0.001	0.175 (0.060, 0.513)	0.004	0.186 (0.060, 0.580)